Steroid Responsive Meningitis (SRMA) in DogsSteroid Responsive Meningitis Arteritis. SRMA is an auto-immune disease that causes inflammation in the layers around the spinal cord called the meninges meningitis and small blood vessels arteritis. It is menignitis common in young large breed dogs and primobolan 100mg dosage most frequently in Beagles, Boxers, and Bernese Mountain dogs. Steroid responsive meningitis symptoms inflammation leads to pain. The most common presentation for SRMA is neck pain but dogs can have pain elsewhere down the spine.
Steroid Responsive Meningitis Arteritis
The meninges are layers of connective tissue that surround the brain, the spinal cord and cerebrospinal fluid CSF , and the arteries and vessels contained within them. Steroid-responsive meningitis-arteritis results in the presence of white blood cells in the CSF and it is suspected by researchers that the immune system may be mistakenly attacking the meninges. The condition is known by many other names including aseptic suppurative meningitis, Beagle pain syndrome, necrotizing vasculitis, and canine juvenile polyarteritis syndrome.
This condition affects young dogs most often with the typical age of onset being 6 to 18 months, but the age range can go up to approximately seven years.
Steroid-responsive meningitis-arteritis SRMA is an inflammatory disease of the central nervous system, affecting the meninges layers of tissue that surround the brain and the meningeal arteries. This is a well-recognised disease in the field of veterinary medicine and the prognosis can be very positive with prompt treatment and aggressive therapy.
The symptoms for SRMA can be chronic or present as flares of an intermittent nature. Your pet may be showing signs of stiffness and pain only to have the symptoms disappear.
It is best to have your canine family member checked by a veterinarian nonetheless because steroid-responsive meningitis-arteritis can lead to serious complications if not attended to. The cause for steroid-responsive meningitis-arteritis is not definitively known but there are concrete suspicions as to why it occurs due to constant research on the condition.
When you bring your canine family member to the clinic the veterinarian will do a physical examination. This will be done with great care as no doubt, your pet is most likely in pain even though he may not display the extent of it to you. Dogs with advanced SRMA will have dramatically increased signs of weakness and possible indications of impending paralytic effects.
Standard tests that may help in the diagnostic process are urinalysis, complete blood count, and serum chemistry. CRP is a marker that is very indicative of an inflammatory process in the body. Radiographs and MRI could be the next steps in the search for a diagnosis.
The veterinarian will need to investigate the stability of the spine which can be compromised in some diseases. The veterinary team will want to rule out illnesses such as discospondylitis, ascertain whether there has been a trauma to the body that could be causing the arched back and pain, and verify that there are no infections or tumors that could bring on intense fever and discomfort.
Once the stability of the spine and joints has been confirmed, a sample of the cerebrospinal fluid will be taken. In addition to checking for bacteria, fungus, or other inflammatory conditions, the analysis of the CSF could indicate that there is an increase in white blood cells.
This factor, along with the physical signs, is very indicative of SRMA. Most cases, however, are beyond mild. Young dogs in the acute phase most commonly seen are treated with anti-inflammatories and long-term immunosuppressive therapy which lasts between a minimum of 4 months up to 20 months in duration.
A canine who has chronic and recurring SRMA will most likely need a drug therapy given on alternating days which will consist of an immunosuppressive drug and a glucocorticoid. Early in the treatment regimen, pain relief may be necessary also.
Follow-up appointments will be very important and absolutely necessary with a diagnosis of steroid-responsive meningitis-arteritis. Your veterinarian will determine the schedule of the return visits which will depend on how well your furry family member responds to the treatment.
The follow-up will mean repeat blood tests and analysis of the CSF until the veterinarian can see that the markers have returned to normal. This could mean appointments every 4 to 6 weeks for several months. It is imperative that you keep the appointments and do not discontinue the medication even though you may think your dog is feeling better. With SRMA there is a potential for relapse, meaning that continued contact with your veterinarian will be recommended.
Gran Mal cluster seizures, sudden onset, 4 times a day. Dx was Antibody flare up, or brain tumor. I was told if she did not respond to Tx that she had months to live, and likely it was a tumor. I could not afford vet care after that so I finished antibiotics and taped pred and pheno. Gran -Mal times a week, lethargic, confused on no meds. Is it common for a dog of this age to have this disorder? Roscoe started with a fever and shivers 2 weeks ago on the 16th The vet prescribed Ciprofloxacin.
He took them for 4 days until the 20th. Acted confused if he walked behind a door, didn't know what to do until we corrected him.
He still ate and drank water and went to the bathroom. We got snowed in from a blizzard on sunday and monday. We were able to get to the vet on tuesday the 23rd.
Fever was gone, but all other issues were still happening. They decided to keep him and he'll have been there for a week tomorrow. Last friday the 26th, he seemed especially bad, eyes had a lot of mucus and watery.
We visited again today and he still seemed confused and lost. Clean eyes, but watery. I was not specifically given the diagnosis of Meningitis, but symptoms seem almost identical. We live in a small town so I'm not sure if a CSF would be available. I know they are treating him with 6 different pills, prednisone, antibiotic and stomach pills for the prednisone effects. Without doing the CSF, is this the best treatment possible?
Also, how long until we would have positive results? I know they usually have to take the prednisone for months afterwards. Sorry for the long description, but thank you for any help and information.
He is on Prednisone, Doxycycline, Famotidine, and Metronidazole. He came home today, after staying at the vets for 9 days. He seems confused, wobbly, restless, but also tired. I know Meningitis can take awhile to recover from. Although I know each dog is different. My dog was diagnosed with this about a month ago when I noticed that she was walking crooked, could not turn her neck, and was not as happy as usual.
After we left her at the vet for a week in the beginning, she came back fine and had been fine until now.
This past week she has been walking even more crooked than before and she seems happy still but not as excited as usual. Sometimes when she's walking, she'll just plop onto the floor and stay like that for a while. Our vet has no idea what's happening to her so I was hoping you may be able to tell me what's wrong.
Our 8 year old blue tick beagle began showing signs of this disease almost 2 years ago. Lately, the pred has really not been doing the job of treating symptoms. He struggles to get up, and walks in tiny, stiff steps. Are there cases of this disease which do not ever get better, and ultimately lead to having to put the dog down? It kills me to even pose the question, but lately, his quality of life is nonexistent, and I imagine is pain level is high.
My dog was diagnosed with SRMA when he was one year old. He recovered well following a course of steroids. He had a small relapse quite soon after finishing the meds so went back on them for a couple of months to ensure he was clear. My vet had prescribed extra steroids for us to keep just in case so we can administer at first sign of it recurring as they are so fast acting. My question is, is he likely to continue to relapse every so often through his life? My 7yo desexed male kelpie has been diagnosed with this, no trace of infection found so immune mediated process likely.
Prior to commencing steroids and antibiotic combo therapy, he was very ill. He had a pretty much immobilising ataxia. It has shown slight improvement after 3 days.
What is the chance of mobility recovery? I dont know if you have control of advertisements on your page, but I think that dog walking adverts that pop up over the posts are quite insensitive. Thank you for your sensitive and honest answer. Mr Traddles is indeed improved today and it feels like hope for at least good enough recovery for him is not misplaced.
Hi could the removal of a saliva gland and loss of blood pressure and haemorrhaging cause SRM in my Maltese shitzu? He was healthy when taken to the vets. We feel the operation could have caused this. The exact etiology of steroid-responsive meningitis-arteritis remains unclear but we believe that it is due to an autoimmune condition since the condition responds to treatment with prednisolone.
I cannot say that the surgery is related as we have little data about the cause of the condition, but it cannot be ruled out. Menu Become a Walker Home. Rated as Serious Condition.
Causes Diagnosis Treatment Recovery Advice. First Walk is on Us! What are Steroid-Responsive Meningitis-Arteritis? Book First Walk Free! Back pain Neck pain Vocalization of the discomfort Fever Lowered head Arched back Stiff gait Rigid stance Depression Lethargy Sometimes there may be muscle spasms Types Acute This is the most common form Presents with pain along the back Typical signs of fever, stiff gait, and rigid back are seen The dog will remain in a hunched position Chronic This can occur as the result of the relapse of an acute attack after treatment Secondary complications to chronic SRMA are many, including muscle weakness, seizures, and loss of bodily control.
There may be a genetic predisposition All breeds can be affected but there is an over-representation in studies of the following breeds: Boxers, Beagles, Weimaraners, Bernese Mountain Dogs, and the Nova Scotia Duck Tolling Retriever The breed disposition may make the prognosis for recovery more guarded for canines of that type Studies show there may be an abnormal immune response to the central nervous system Researchers think there could be a link between a genetic reaction to the environment The condition can accompany immune-mediated polyarthritis suggesting a possible connection Some researchers feel there may be a link between vaccinations and the possible desensitization of the dog to viral antigens There could be a relation to age as older dogs can be less responsive to treatment.
Has Symptoms Goose walk. Left hind leg slow reflex.