Medical marijuana (also called medical cannabis) is whole plant marijuana or chemicals in the plant used for medical purposes. The two main cannabinoids used in medicine are tetrahydrocannabinol (THC) and cannabidiol (CBD). Medical cannabis, CBD, and THC all have possible side. However, in the case of weed I do not not if it does have any interference or not. .. I saw it as the only way that epilepsy could make me cool, that i could actually . The change in law means that specialist doctors in the UK can now prescribe medicinal cannabis to people with a limited number of conditions.
Can Seizures Cannabis Calm
At least some of them reported similarly miraculous responses to it. So when we reported earlier this month that a new National Academy of Sciences report—the most in-depth analysis of marijuana research to date—concluded that there was not enough evidence to say that cannabis oil could actually treat epilepsy, some people were surprised:.
How could the panel draw such a conclusion? Because readers asked, and because this particular conclusion one of almost that the academy drew from their scientific review is a good window into the whole report and the larger debate surrounding medical marijuana, we decided to take a closer look. The reviewers restricted their evaluation to studies that involved humans, excluding any evidence from studies done on animals.
But limiting the studies in this way left the reviewers with some pretty slim pickings. The largest of those studies included a total of patients, treated with 99 percent CBD oil extract for 12 weeks; it found that CBD worked about as well as existing anti-epilepsy medications do in treatment-resistant sufferers. CBD reduced seizures by a monthly average of First, there was simply not enough of that kind of evidence.
FDA-approved drugs are usually deemed effective or ineffective based on large-scale clinical trials that study hundreds to thousands of patients over several years. These studies followed only a few hundred patients in all, and for only a few months. Second, the studies in question did not include placebo controls. That is, all of the study participants were given actual CBD, and they knew they were getting it. Other research has found that the placebo effect can be especially strong when it comes to marijuana.
In one study, patients of families who moved to Colorado for cannabis oil treatment were twice as likely to report a substantial reduction in seizures as those patients who already lived in the state. The third major reason the studies were deemed insufficient involves drug interactions.
This drug interaction makes it impossible to say whether reduced seizure incidence seen in study participants was due to CBD by itself or whether it was simply the result of those other medications staying in the system for longer stretches. The good news is that higher-quality randomized clinical trials that examine the effectiveness of CBD oil for epilepsy are underway some have even been completed , and the results should be published sometime this year.
In the meantime, there are a few things to keep in mind if you or your child suffers from intractable seizures and you're considering trying cannabis oil. First is that, as we've written before, medical marijuana or cannabis products are not subject to the same regulations as FDA-approved drugs.
Derivatives of marijuana high in CBD but with negligible amount of THC might offer some benefit for intractable epilepsy. These compounds might provide the benefits without some of the risks—or the legal issues—associated with the marijuana plant. For one thing, cannabis is still listed as a Schedule I substance by the federal government, meaning gaining permission to use it in research on human participants is extremely difficult. Still, change is occurring at the state level. Recreational marijuana use is legal for adults in four states Alaska, Colorado, Oregon, and Washington and in 23 states and Washington, DC, medical marijuana is allowed.
Texas, in a law passed during the last legislative session in , legalized low-THC cannabis oils for people with intractable epilepsy while still prohibiting medical marijuana more broadly. The researchers will compare the genetics of those who have seen seizure activity decreased dramatically at least 50 percent in response to the drug versus those who did not. Although this research could yield useful information about how CBD and genetic factors interact in a Dravet population, it is not the gold standard of scientific drug trials: Certain treatments that are effective for one type of epilepsy can be ineffective for or even worsen other types of epilepsy.
Scientific studies in people with epilepsy help us to understand how and why various treatments work, and for whom they are effective. Research also helps us understand the correct dose, side effects and potential interactions with other medications. The research needed to determine if marijuana derivatives are safe and effective for the treatment of children or adults with epilepsy cannot occur without funding.
At the present time it is difficult, if not impossible, to obtain federal funding to complete research on medical marijuana due to the designation of marijuana as a DEA schedule 1 drug. It is imperative that these studies be performed by medical researchers who have expertise in pediatric epilepsy and know how to conduct clinical research studies.
It's also critical that these investigators have no financial interest in the results of these studies, so that the public can have the utmost confidence that the resulting findings are valid and unbiased. Physicians and patients and their families need all the necessary information to make the best decisions regarding care. We understand first-hand the medical complexity of epilepsy and the difficult decisions facing people with epilepsy and their families.
We urge all people touched by epilepsy to consult with an epilepsy specialist and explore the many existing treatment options to empower them to make informed decisions with their specialist that weighs the risks and benefits of the different treatment options. Learn more about medical marijuana and our Neuroscience Institute. Facebook Twitter LinkedIn Print. Do we prescribe medical marijuana? Is marijuana helpful in the treatment of epilepsy?
Cannabis for epilepsy: is there enough evidence of efficacy?
While this case can illustrate medical cannabis' ability to help treat seizures, it is important to understand how this worked and whether it's. Parents are turning to medical marijuana to help children plagued by epileptic seizures. But how much scientific evidence is there to suggest it. Could a plant that was introduced to the United States by early settlers provide relief for people with epilepsy today? Marijuana (Cannabis.